Glucagon-like peptide-1 receptor signaling modifies the extent of diabetic kidney disease through dampening the receptor for advanced glycation end products-induced inflammation.
Sourris KC, Ding Y, Maxwell SS, Al-Sharea A, Kantharidis P, Mohan M, Rosado CJ, Penfold SA, Haase C, Xu Y, Forbes JM, Crawford S, Ramm G, Harcourt BE, Jandeleit-Dahm K, Advani A, Murphy AJ, Timmermann DB, Karihaloo A, Knudsen LB, El-Osta A, Drucker DJ, Cooper ME, Coughlan MT.. Kidney International. 2024;105:132-149.
Minireview: Understanding and targeting inflammatory, hemodynamic and injury markers for cardiorenal protection in type 1 diabetes.
Interferons and interferon-related pathways in heart disease.
Tran DT, Batchu SN, Advani A. Frontiers in Cardiovascular Medicine. 2024;11:1354343.
Preventing occludin tight-junction disruption via inhibition of microRNA-193b-5p attenuates viral load and influenza-induced lung injury.
Vaswani CM, Varkouhi AK, Gupta S, Ektesabi AM, Tsoporis JN, Yousef S, Plant PJ, da Silva AL, Cen Y, Tseng YC, Batah SS, Fabro AT, Advani SL, Advani A, Leong-Poi H, Marshall JC, Garcia CC, Rocco PRM, Albaiceta GM, Sebastian-Bolz S, Watts TH, Moraes TJ, Capelozzi VL, Dos Santos CC. Molecular Therapy. 2023;31:2681-2701.
Altered expression, but small contribution, of the histone demethylase KDM6A in obstructive uropathy in mice.
Hong LYQ, Yeung ESH, Tran DT, Yerra VG, Kaur H, Kabir MDG, Advani SL, Liu Y, Batchu SN, Advani A. Disease Models & Mechanisms. 2023;16:dmm049991.
Pressure overload induces ISG15 to facilitate adverse
ventricular remodeling and promote heart failure
Yerra VG, Batchu SN, Kaur H, Kabir MDG, Liu Y, Advani
SL, Tran DT, Sadeghian S, Sedrak P, Billia F, Kuzmanov
U, Gramolini AO, Qasrawi DO, Petrotchenko EV, Borchers
CH, Connelly KA, Advani A. The Journal of Clinical Investigation. 2023;133:e161453.
Single cell G-protein coupled receptor profiling of
Transcription factor 21 expressing activated kidney
fibroblasts
Kaur H, Yerra VG, Batchu SN, Tran DT, Kabir MDG, Liu Y,
Advani SL, Sedrak P, Geldenhuys L, Tennankore KK, Poyah
P, Siddiqi FS, Advani A. British Journal of Pharmacology. 2023;133:Epub ahead of print April 28.
The anti-hypertensive effects of sodium-glucose
cotransporter-2 inhibitors.
Kugathasan L, Dubrofsky L, Advani A, Cherney DZI. Expert Reviews in Cardiovascular Therapy. 2023;21:15-34.
Sustained improvement in glycemic control in emerging
adults with Type 1 diabetes 2 years after the start of
the COVID-19 pandemic.
Swaich H, Advani A. Diabetes Therapy. 2023;14:153-165.
The SGLT2i dapagliflozin reduces RV mass independent of
changes in RV pressure induced by pulmonary artery
banding.
Connelly KA, Wu E, Visram A, Friedberg MK, Batchu SN,
Yerra VG, Thai K, Nghiem L, Zhang Y, Kabir G, Desjardins
JF, Advani A, Gilbert RE. Cardiovascular Drugs and Therapy. 2022;
Epub ahead of print Sep 29.
DJ-1 binds to rubicon to impair LC-3 associated
phagocytosis.
Gupta S, Amatullah H, Tsoporis JN, Wei K, Monteiro APT,
Ektesabi AM, Varkouhi AK, Vaswani CM, Formosa A, Fabro
AT, Batchu SN, Fjell C, Russell JA, Walley KR, Advani A,
Parker TG, Marshall JC, Rocco PRM, Fairn GD, Mak TW, Dos
Santos CC. Cell Death and Differentiation. 2022;29:2024-2033.
Role of CCR2-positive cardiac macrophages in
pathological ventricular remodeling.
Yerra VG, Advani A. Biomedicines. 2022;10:661.
Perceptions and correlates of distress due to the
COVID-19 pandemic and stress management strategies among
people with diabetes: a mixed methods study.
Im J, Escudero C, Zhang K, Choi D, Sivakumar A, Booth
GL, Sale J, Pritlove C, Advani A, Yu CH. Canadian Journal of Diabetes. 2022;46:253-261.
Empagliflozin disrupts a Tnfrsf12a-mediated feed forward
loop trial that promotes left ventricular hypertrophy.
Yerra VG, Batchu SN, Kabir G, Advani SL, Liu Y, Siddiqi
FS, Connelly KA, Advani A. Cardiovascular Drugs and Therapy. 2022;36:619-632
Lung and kidney ACE2 and TMPRSS2 in renin angiotensin
system blocker treated comorbid diabetic mice mimicking
host factors that have been linked to severe COVID-19.
Batchu SN, Kaur H, Yerra VG, Advani SL, Kabir MG, Liu Y,
Klein T, Advani A. Diabetes. 2021;70:759-771.
Acute kidney injury: a bona fide complication of
diabetes. Diabetes.
Advani A. Diabetes. 2020;69:2229-2237.
Experiences and perspectives of the parents of emerging
adults living with type 1 diabetes.
Pritlove C, Markowitz B, Mukerji G, Advani A*, Parsons
JA*. BMJ Open Diabetes Research and Care. 2020;e001125.
The dipeptidyl peptidase-4 inhibitor linagliptin
directly enhances the contractile recovery of mouse
hearts at a concentration equivalent to that achieved
with standard dosing in humans.
Batchu SN, Yerra VG, Liu Y, Advani SL, Klein T, Advani
A. IJMS 2020;21:E5757.
A common glomerular transcriptomic signature
distinguishes diabetic kidney disease from other kidney
diseases in humans and mice. Current Research in
Abdalla M, Abdalla M, Siddiqi FS, Geldenhuys L, Batchu
SN, Tolosa MF, Yuen DA, Dos Santos CC, Advani A. Translational Medicine. 2020;S2452-3186:30034-30039.
Acute kidney injury: a bona fide complication of
diabetes.
Advani A. Diabetes. 2020;69:2229-2237.
Experiences and perspectives of the parents of emerging
adults living with type 1 diabetes.
Pritlove C, Markowitz B, Mukerji G, Advani A, Parsons
JA. BMJ Open Diabetes Research and Care. 2020;8:e001125.
The dipeptidyl peptidase-4 inhibitor linagliptin
directly enhances the contractile recovery of mouse
hearts at a concentration equivalent to that achieved
with standard dosing in humans.
Batchu SN, Yerra VG, Liu, Y, Advani SL, Klein T, Advani
A. IJMS. 2020;21:E5757.
A common glomerular transcriptomic signature
distinguishes diabetic kidney disease from other kidney
diseases in humans and mice.
Abdalla M, Abdalla M, Siddiqi FS, Geldenhuys L, Batchu
SN, Tolosa MF, Yuen DA, Dos Santos CC, Advani A. Current Research in Translational Medicine. 2020;S2452-3186:30034-30039.
Screening and treatment outcomes in adults and children
With Type 1 Diabetes and asymptomatic celiac disease:
The CD-DIET Study.
Mahmud FH, Clarke ABM, Joachim KC, Assor E, McDonald C,
Saibil F, Lochnan HA, Punthakee Z, Parikh A, Advani A,
Shah BR, Perkins BA, Zuijdwijk CS, Mack DR, Koltin D, De
Melo EN, Hsieh E, Mukerji G, Gilbert J, Bax K, Lawson
ML, Cino M, Beaton MD, Saloojee NA, Lou O, Gallego PH,
Bercik P, Houlden RL, Aronson R, Kirsch SE, Paterson WG,
Marcon MA. Diabetes Care. 2020;43:1553-1556.
Load-independent effects of empagliflozin contribute to
improved cardiac function in experimental heart failure
with reduced ejection fraction.
Connelly KA, Zhang Y, Desjardins JF, Ngheim L, Visram A,
Batch SN, Yerra VG, Kabir G, Thai K, Advani A, Gilbert
RE. Cardiovascular Diabetology. 2020;19:13.
The endothelial barrier is not rate-limiting to insulin
action in the myocardium of male mice.
Sanwal R, Khosraviani N, Advani SL, Advani A, Lee WL. Endocrinology. 2020;161:bqaa029.
Feb 27.
Positioning time in range in diabetes management.
Advani A. Diabetologia. 2020;63:242-252.
Dysregulated expression but redundant function of the
long non-coding RNA HOTAIR in diabetic kidney disease.
Majumder S, Hadden MJ, Thieme K, Batchu SN, Niveditha D,
Chowdhury S, Yerra VG, Advani SL, Bowskill BB, Liu Y,
Vakili H, Alghamdi TA, White KE, Geldenhuys L, Siddiqi
FS, Advani A. Diabetologia. 2019;62:2129-2142.
The 3i conceptual framework for recognizing patient
perspectives of Type 1 diabetes during emerging
adulthood.
Empagliflozin improves diastolic function in a
nondiabetic rodent model of heart failure with preserved
ejection fraction.
Connelly KA, Zhang Y, Visram A, Advani A, Batchu SN,
Desjardins JF, Thai K, Gilbert RE. JACC Basic to Translational Science. 2019;25:27-37.
Renal hemodynamic function and RAAS activation over the
natural history of Type 1 diabetes.
Lytvyn Y, Bjornstad P, Lovshin JA, Boulet G, Farooqi MA,
Lai V, Tse J, Cham L, Lovblom LE, Weisman A, Keenan HA,
Brent MH, Paul N, Bril V, Advani A, Sochett E, Perkins
BA, Cherney DZI. American Journal of Kidney Diseases. 2019;73:786-796.
Association between uric acid, renal hemodynamics and
arterial stiffness over the natural history of type 1
diabetes.
Lytvyn Y, Bjornstad P, Lovshin JA, Singh SK, Boulet G,
Farooqi MA, Lai V, Tse J, Cham L, Lovblom LE, Weisman A,
Keenan HA, Brent MH, Paul N, Bril V, Advani A, Sochett
E, Perkins BA, Cherney DZI. Diabetes, Obesity and Metabolism. 2019;21:1388-1398.
